Diedre Nienow

All articles from this author are listed below.

Volume 9, Number 4 Review Articles

Extending the Rationale of Combination Therapy to Unresponsive Erectile Dysfunction

Treatment Update

Rajeev Kumar Ajay Nehra Diedre Nienow Christopher Reece

Combination therapies aim to overcome the limitations of individual drugs by selecting diverse targets of action to enhance effectiveness synergistically. This article reviews the principles of combination therapy and its applications for benign prostatic hyperplasia and overactive bladder. It then examines pathophysiological, pharmacological, and clinical evidence for currently available drug and device combinations for erectile dysfunction that has not responded to first-line, single-agent therapy. [Rev Urol. 2007;9(4):197-206]

Benign prostatic hyperplasia Overactive bladder Erectile dysfunction Combination therapy Intracavernosal therapy Intraurethral therapy