Frank L. Spangler

All articles from this author are listed below.

Volume 24, Number 1 Reviews in Urology

Evaluating the Analytical Validity and Clinical Utility and Validity of Polymerase Chain Reaction Diagnostics vs Culture and Sensitivity Methods in Complicated Urinary Tract Infection Management

A Comprehensive Review of Real-World Evidence, Clinical Trials, and MetaAnalyses Concerning Molecular Diagnostic Services Program Coverage Criteria

Michael E. Aberger Bradley A. Wilson Roel Chavez Frank L. Spangler Itoe P. Priestly Lauren Y. Park Moustafa Kardjadj

Polymerase chain reaction (PCR)–based diagnostics are increasingly used for complicated urinary tract infections, offering faster and more sensitive detection of pathogens than conventional culture and sensitivity methods. This review assessed the clinical validity, utility, and alignment of PCR-based diagnostics with the Molecular Diagnostic Services Program’s (MolDX) Medicare coverage and reimbursement criteria.

Polymerase chain reaction microbial sensitivity tests validation study insurance health reimbursement Urinary tract infections